Proton MR spectroscopy and imaging of a galactosemic patient before and after dietary treatment.

نویسندگان

  • M C G Otaduy
  • C C Leite
  • M T C Lacerda
  • M O R Costa
  • F Arita
  • E Prado
  • S Rosemberg
چکیده

We describe how proton MR spectroscopy ((1)H-MR spectroscopy) was useful in elucidating the diagnosis of galactosemia in an undiagnosed 6-month-old infant. In vivo (1)H-MR spectroscopy of the brain showed a doublet at 3.7 parts per million, which was identified as galactitol (Gal-ol) by in vitro (1)H-MR spectroscopy of the urine. Galactosemia was subsequently confirmed by laboratory tests and treatment was initiated. A follow-up brain MR imaging and (1)H-MR spectroscopy study revealed resolution of white matter lesions and disappearance of Gal-ol peaks.

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عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 27 1  شماره 

صفحات  -

تاریخ انتشار 2006