Proton MR spectroscopy and imaging of a galactosemic patient before and after dietary treatment.
نویسندگان
چکیده
We describe how proton MR spectroscopy ((1)H-MR spectroscopy) was useful in elucidating the diagnosis of galactosemia in an undiagnosed 6-month-old infant. In vivo (1)H-MR spectroscopy of the brain showed a doublet at 3.7 parts per million, which was identified as galactitol (Gal-ol) by in vitro (1)H-MR spectroscopy of the urine. Galactosemia was subsequently confirmed by laboratory tests and treatment was initiated. A follow-up brain MR imaging and (1)H-MR spectroscopy study revealed resolution of white matter lesions and disappearance of Gal-ol peaks.
منابع مشابه
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
PURPOSE To compare the MR imaging and MR angiographic changes with in vivo proton MR spectroscopic findings and to determine the spectral differences between edema and ischemia in patients with eclampsia. METHODS Spin-echo MR imaging, MR angiography, and single-voxel proton MR spectroscopy were performed in 10 patients with eclampsia. MR studies were obtained within 3 to 5 days of diagnosis a...
متن کاملComparison between MRS and DWI in MRI of breast cancer
Introduction: Breast cancer is the most common cancer in women and is the second leading cause of cancer death (after lung cancer) in people throughout the world. Today, MRI is being used because of the limitations of x-ray mammography to detect breast cancer. Non-contrast sequences were associated to CE sequences in a breast MRI protocol for the sake of appraising morphologic ...
متن کاملEvaluation of treatment-induced cerebral white matter injury by using diffusion-tensor MR imaging: initial experience.
BACKGROUND AND PURPOSE Treatment with chemotherapy and radiation therapy for brain tumors can cause white matter (WM) injury. Conventional MR imaging, however, cannot always depict treatment-induced transient WM abnormalities. We investigated the ability of diffusion-tensor (DT) MR imaging and proton MR spectroscopy to detect the treatment-induced transient changes within normal-appearing WM. ...
متن کاملSerial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery.
BACKGROUND AND PURPOSE The diagnosis of brain tumors after high-dose radiation therapy is frequently limited by the lack of metabolic discrimination available with conventional imaging methods. The purpose of this study was to use proton MR spectroscopy to investigate serial changes in recurrent malignant gliomas after gamma knife radiosurgery to characterize tissue response to high-dose radiat...
متن کاملWhite matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
PURPOSE The purpose of this study was to determine the time course for development of white matter changes induced by high-dose chemotherapy. METHODS Eight patients with advanced breast cancer were entered into a prospective, longitudinal trial that included examination by MR imaging and proton MR spectroscopy before chemotherapy and through 12 months after treatment with carmustine, cyclopho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 27 1 شماره
صفحات -
تاریخ انتشار 2006